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Karl Messlinger Selected Research

Calcitonin Gene-Related Peptide Receptors (Calcitonin-Gene Related Peptide Receptor)

3/2018The big CGRP flood - sources, sinks and signalling sites in the trigeminovascular system.
1/2018Effect of a calcitonin gene-related peptide-binding L-RNA aptamer on neuronal activity in the rat spinal trigeminal nucleus.
11/2013The calcitonin gene-related peptide receptor antagonist MK-8825 decreases spinal trigeminal activity during nitroglycerin infusion.
9/2013Changes in calcitonin gene-related peptide (CGRP) receptor component and nitric oxide receptor (sGC) immunoreactivity in rat trigeminal ganglion following glyceroltrinitrate pretreatment.
10/2012CGRP and NO in the trigeminal system: mechanisms and role in headache generation.
1/2011Neuropeptide effects in the trigeminal system: pathophysiology and clinical relevance in migraine.
12/2009Glyceroltrinitrate facilitates stimulated CGRP release but not gene expression of CGRP or its receptor components in rat trigeminal ganglia.
11/2009Calcitonin gene-related peptide receptor antagonist olcegepant acts in the spinal trigeminal nucleus.
3/2008Calcitonin receptor-like receptor (CLR), receptor activity-modifying protein 1 (RAMP1), and calcitonin gene-related peptide (CGRP) immunoreactivity in the rat trigeminovascular system: differences between peripheral and central CGRP receptor distribution.
6/2006Inhibition of stimulated meningeal blood flow by a calcitonin gene-related peptide binding mirror-image RNA oligonucleotide.

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Karl Messlinger Research Topics

Disease

22Headache (Headaches)
02/2022 - 09/2004
19Migraine Disorders (Migraine)
01/2022 - 06/2005
8Pain (Aches)
01/2020 - 02/2001
3Myocardial Ischemia (Ischemic Heart Diseases)
12/2006 - 02/2005
2Neoplasms (Cancer)
01/2019 - 01/2012
2Tension-Type Headache (Tension Headache)
12/2016 - 10/2014
2Ganglion Cysts (Ganglion)
01/2011 - 10/2008
1Erythema
10/2022
1Hypoxia (Hypoxemia)
11/2021
1Edema (Dropsy)
01/2019
1Neurogenic Inflammation
04/2017
1Heart Failure
07/2014
1Hemorrhage
07/2013
1Osteonecrosis (Kienbock's Disease)
01/2012
1Cluster Headache (Cluster Headaches)
01/2011
1Diabetes Mellitus
12/2006
1Vascular Headaches (Vascular Headache)
11/2002

Drug/Important Bio-Agent (IBA)

23Calcitonin Gene-Related PeptideIBA
01/2022 - 11/2002
10Calcitonin Gene-Related Peptide Receptors (Calcitonin-Gene Related Peptide Receptor)IBA
03/2018 - 06/2006
9Nitric Oxide (Nitrogen Monoxide)FDA Link
04/2017 - 11/2002
5Vasodilator Agents (Vasodilators)IBA
01/2022 - 02/2005
4NeuropeptidesIBA
01/2022 - 01/2011
4Pharmaceutical PreparationsIBA
12/2020 - 01/2012
3nitroxylIBA
02/2022 - 07/2014
3Calcitonin Gene-Related Peptide Receptor AntagonistsIBA
07/2012 - 11/2009
2Biomarkers (Surrogate Marker)IBA
11/2021 - 04/2021
2Substance PIBA
01/2019 - 01/2011
2AntibodiesIBA
03/2018 - 01/2018
2naratriptanFDA LinkGeneric
02/2014 - 02/2001
2Nitroglycerin (Dynamite)FDA LinkGeneric
11/2013 - 09/2013
2Nitric Oxide Synthase (NO Synthase)IBA
10/2012 - 10/2008
2Morphine (MS Contin)FDA LinkGeneric
04/2009 - 12/2003
1oxyhyponitriteIBA
02/2022
1Monoclonal AntibodiesIBA
01/2022
1Glycerol (Glycerine)FDA LinkGeneric
01/2022
1isopetasinIBA
04/2021
1petasinIBA
04/2021
1Phenylephrine (Neo-Synephrine)FDA LinkGeneric
01/2020
1TRPV1 receptorIBA
01/2020
1CalciumIBA
01/2020
1Neuropeptide Receptors (Neuropeptide Receptor)IBA
11/2019
1Nerve Growth Factors (Neurotrophins)IBA
11/2019
1Dinoprostone (PGE2)FDA Link
01/2019
1Biological ProductsIBA
01/2019
1Immunoglobulin G (IgG)IBA
03/2018
11-(3-chlorophenyl)piperazineIBA
04/2017
1Blood Proteins (Serum Proteins)IBA
04/2017
1Serotonin (5 Hydroxytryptamine)IBA
04/2017
15-HT2B Serotonin ReceptorIBA
04/2017
1Hydrogen Sulfide (Sulfide, Hydrogen)IBA
01/2017
1Cholinergic Agents (Cholinergics)IBA
01/2017
1Adenosine Triphosphate (ATP)IBA
12/2016
1Capsaicin (Zostrix)FDA Link
02/2014
1Tuberculin (PPD)IBA
07/2013
1Diphosphonates (Bisphosphonates)IBA
01/2012
1Sunitinib (Sutent)FDA Link
01/2012
1Bevacizumab (Avastin)FDA Link
01/2012
1Vasoactive Intestinal Peptide (VIP (Vasoactive Intestinal Peptide))IBA
01/2011
1Proteins (Proteins, Gene)FDA Link
01/2011
1telcagepantIBA
11/2009
1olcegepantIBA
11/2009
1Analgesics (Analgesic Drugs)IBA
12/2003

Therapy/Procedure

8Therapeutics
01/2022 - 06/2006
1Lasers (Laser)
10/2022
1Occlusal Splints
10/2014
1Musculoskeletal Manipulations (Manipulative Therapy)
09/2013
1Dental Care
01/2012
1Drug Therapy (Chemotherapy)
01/2012
1Cardiopulmonary Bypass (Heart-Lung Bypass)
12/2006